Vitamin Supplements Formulation
Learn to formulate and encapsulate vitamin supplements safely.
Materials & Tools Needed
Step-by-Step Instructions
Research and Plan Formula
Research recommended daily allowances (RDA) and safe upper limits for each vitamin. Plan your formulation ensuring no ingredient exceeds safe levels.
💡 Pro Tip
Consult with nutritionists and follow FDA dietary supplement guidelines.
Source Quality Ingredients
Purchase pharmaceutical-grade vitamin powders from reputable suppliers with certificates of analysis. Verify identity and purity of all ingredients.
Calculate Capsule Capacity
Determine capsule size needed based on total powder volume. Size 00 holds ~735mg, size 0 holds ~500mg. Account for powder density differences.
Prepare Clean Workspace
Set up workspace following good manufacturing practices. Clean all equipment with appropriate sanitizers. Wear gloves, hairnet, and lab coat.
Weigh Ingredients Precisely
Using a calibrated analytical scale, weigh each vitamin powder according to your formula. Double-check all measurements for accuracy.
Add Excipients
Mix in appropriate flow agents (like silicon dioxide) and fillers (like rice flour) to improve powder flow and fill capsules to proper capacity.
Blend Uniformly
Thoroughly mix all powders using geometric dilution method. Start with smallest quantity ingredients, gradually incorporating larger volumes.
Test Blend Uniformity
Take samples from different areas of the blend and test for content uniformity. Remix if variation exceeds 5% from target.
Prepare Capsule Machine
Set up manual or semi-automatic capsule filling machine. Separate capsule halves and place body sections into machine holder plate.
Fill Capsules
Spread vitamin blend over capsules and use tamping tool to fill bodies. Level off excess powder and place capsule caps on bodies.
Quality Control and Package
Weigh filled capsules for consistency (±10% variation acceptable). Package in appropriate bottles with desiccants, tamper-evident seals, and proper labeling.